Features of idiopathic pulmonary alveolar proteinosis in high resolution computed tomography

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Features of idiopathic pulmonary alveolar proteinosis in high resolution computed tomography

BACKGROUND Although the crazy-paving pattern on computed tomography is characteristic for pulmonary alveolar proteinosis (PAP), it is not specific and has not been compared between idiopathic and secondary PAPs in the large studies. The aim of this study was to determine the high resolution computed tomography (HRCT) features of idiopathic PAP. MATERIAL/METHODS HRCT images of 35 patients (mea...

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Segmentation-Based Quantitation of Pulmonary Alveolar Proteinosis, Pre- and Post-Lavage, Using High-Resolution Computed Tomography

Pulmonary alveolar proteinosis is a disorder of surfactant deposition that leads to the accumulation of lipoproteinaceous material in the alveoli. The mainstay of treatment is whole-lung lavage, by which saline is used to wash the alveolar deposits from the lung. Patients are currently followed using sequential preand post-lavage CT to subjectively assess treatment efficacy. We present an appro...

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High-Resolution Computed Tomography in Idiopathic Pulmonary Fibrosis

Department of Radiology, and Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center; National Jewish Medical and Research Center, Denver, Colorado; Department of Radiology, and Division of Pulmonary and Critical Care Medicine, University of Washington Medical Center, Seattle, Washington; Clinical Science and Biometrics Departments, InterMune, In...

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Serological diagnosis of idiopathic pulmonary alveolar proteinosis.

Previously, we reported the specific occurrence of neutralizing autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF) in the bronchoalveolar lavage fluid from 11 Japanese patients with idiopathic pulmonary alveolar proteinosis (I-PAP). The autoantibody was also detected in sera from all 5 I-PAP patients examined. To determine that the existence of the autoantibody is ...

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Clinical Features and Outcomes of Idiopathic Pulmonary Alveolar Proteinosis in Korean Population

Idiopathic pulmonary alveolar proteinosis (PAP) is a rare disorder in which lipoproteinaceous material accumulates within alveoli. There were few reports on Asian populations with idiopathic PAP. We retrospectively reviewed 38 patients with idiopathic PAP in Korea. We assessed clinical features, therapeutic efficacy and outcomes of whole lung lavage in patients with idiopathic PAP. The mean age...

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ژورنال

عنوان ژورنال: Polish Journal of Radiology

سال: 2014

ISSN: 0137-7183

DOI: 10.12659/pjr.890218